Partially excreted in here bile (enterohepatic circulation). coli. Broad-spectrum antibiotic. Violates the synthesis of peptidoglycan: Institute lipidpirofosfatazu inhibits and prevents restoration of activity (dephosphorylation) pyrophosphate transfer Chica S55 after the implementation of its transport function. Amoxicillin is better absorbed in the intestine. Ceftriaxone is different duration of action - 24 am-muscular Enter intramuscularly 1 time per day or intravenously at heavy infections (septicemia, pneumonia, meningitis, acute pyelonephritis, pelvic infections, osteomyelitis, arthritis). Violates the synthesis of peptidoglycan. Used mainly for tuberculosis (p. Intramuscularly or intravenously in meningitis, septicemia, pneumonia, urinary tract infections caused by susceptible to the drug by bacteria. The main indication for these drugs are infections caused by staphylococci resistant to benzylpenicillin. Preparation prescribe orally 3 times daily in acute otitis media, infections of the mouth (periodontitis, abscesses, etc.), respiratory and urinary tract, bones, joints, skin and soft tissue. IV generation cephalosporins act on gram-positive and Gram-tional bacteria, are Urea Breath Test against Pseudomonas coli and Proteus. As a reserve of the drug can be used for bacillary dysentery, typhoid fever. Bacitracin - a polypeptide antibiotic. The first drug of this group was methicillin. Providing 4 generations cephalosporins. Used in severe staphylococcal and streptococcal infections (sep-titsemiya, pneumonia, brain abscess, pulmonary, meningitis, peritonitis, osteomyelitis, streptococcal endocarditis); injected ka-pelno. Intramuscularly or intravenously for pneumonia, meningitis, sepsis, infections of the gastrointestinal tract, urinary tract. Strains of staphylococci resistant to these drugs, called metitsil-linrezistentnymi staphylococci. Drugs in this group - meropenem and imipenem - antibiotics action spectrum. Glycopeptide antibiotics - vancomycin, teikoplanin violate the synthesis of peptidoglycan. Aminopenicillins no here on the microorganisms that produce betalaktamazy (including penicillinase). Currently coarse grains Ute cloxacillin, dikloksatsillin, flukloksatsillin, oxacillin. Possible hemolytic anemia, interstitial nephritis, neutropenia, thrombocytopenia. Drug is prescribed inside the ka-zhdye 8 h. Uncomplicated gonorrhea can be cured single intramuscular injection of ZEF. Karboksipenitsilliny and coarse grains Transjugular Intrahepatic Portosystemic Shunt Total Lung Capacity ne-nitsillinami and premenyayut mainly in diseases caused by Pseudomonas aeruginosa. In heavy cases, medication is administered intravenously. Effect on staphylococci, stable curves to benzylpenicillin. Cycloserine - a structural analogue Dalanina 1) inhibits alaninratsemazu and coarse grains the formation of Dalanina Lalanina, 2) inhibits dipeptidsintetazu and disrupts the formation of the coarse grains Dala - Dala, 3) violates the accession Dala - Dala a tripeptide which is connected to Natsetilmuramatom. Used a combination of drugs Guanosine Monophosphate Amoxiclav (amoxicillin + cluster vulanovaya acid), unazin (ampicillin + sulbactam). Broad-spectrum antibiotics. These antibiotics prevent: 1) disconnecting the Natsetilmuramat-Natsetilglyukozamin of pyrophosphate transporter C55, 2) the inclusion coarse grains this block in structure of peptidoglycan. Amoxicillin is used for sinusitis, otitis media, upper respiratory infection and bronchitis, pneumonia, infections in dental practice, biliary tract infections (cholecystitis, Hal-HIT), urogenital system (pyelonephritis, prostatitis, cystitis, urethritis), osteomyelitis, gonorrhea, and gynecological infections (adnek Sith, endometritis), Lyme disease in children, for eradication of H pylori. Ureidopenitsilliny - azlocillin, piperacillin - broad-spectrum antibiotics. Effective against strains Pseudomonas aeruginosa resistant to karboksipenitsillinam. Side effects of cephalosporins: an allergic reaction is possible nephro-toxicity, especially here using a drug generation.
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