hr. lymph and miyeloleykozy, limfohranulomatoz, granulocytopenia, thrombocytopenic purpura, flux marrow dysfunction, Mts Family History with autoimmune phenomena panmiyelopatiya, secondary thrombocytopenia in adults, liver disease - hepatitis, hepatic coma, gastrointestinal disease - ulcerative colitis, granulomatous enteritis (Crohn's disease), hlyutenova disease, kidney and urinary tract: with nephrotic-m lypoyidnyy nephrosis in children, urogenital tuberculosis, Retroperitoneal fibrosis, urethral stricture, and g. Glucocorticoids. The main pharmaco-therapeutic action: the GCS belongs to a group of natural origin and has antishock, flux immunosuppressive, antiexudative, protysverbizhnu, inflammatory, desensitizing, antiallergic effect; inhibits hypersensitivity reactions, proliferative and exudative processes in the focus of inflammation; hydrocortisone action mediated through specific intracellular receptors, anti-inflammatory action is inhibition of all phases of inflammation - the stabilization of cellular and subcellular membranes, flux the release of proteolytic enzymes from lysosomes, inhibition of formation superoksydnoho anion and other free radicals, inhibits the release of inflammation mediators, including interleukin-1 (IL-1), histamine, Packed Cell Volume Treatment bradykinin, and others. inflammatory joint diseases - arthritic and psoriatic arthritis, osteoarthritis, polyarthritis, plecholopatkovyy parasynovitis, ankylosing spondylitis (Bechterew disease), juvenile arthritis, CM Stilla in adults kolahenozy - systemic lupus erythematosus, acute disseminated myositis, scleroderma, nodular periarteriyit; allergic diseases - asthma , hay fever, angioneurotic edema, anaphylactic shock, urticaria, pollinosis, drug allergy, subacute thyroiditis, diseases of the respiratory system: pulmonary fibrosis, sarcoidosis, false grains at larynhotraheobronhitah, acute alveolitis, pulmonary tuberculosis, aspiration pneumonia, berylliosis, lung cancer; heart disease: myocarditis, pericardial effusion, postinfarction c-m with pericarditis, decreased arousal threshold in patients with artificial pacemaker; violation Hematologic - hemolytic anemia, erytroblastopeniya (erythrocyte anemia), congenital (erythroid) hypoplastic anemia, agranulocytosis, G. nonspecific tendosynovit, ankylosing spondylitis, epikondylit, posttraumatic osteoarthritis, psoriatic arthritis, RA, including Juvenile RA synovitis osteoarthrosis), systemic connective tissue disease - G. Contraindications to the use of drugs: systemic fungal diseases, hypersensitivity to components of the drug. Pharmacotherapeutic group: H02AB09 - Corticosteroids for systemic use. Pharmacotherapeutic group: N02AA02 - Corticosteroids for systemic Write on label Mineralocorticoid hormone. Heart failure, decompensated diabetes, severe myopathy, osteoporosis, polio (excluding entsefalitychnoyi-bulbar form), systemic mycosis, viral infection, vaccination during the active form of tuberculosis, glaucoma, productive symptoms in mental illness, hypersensitivity to the drug component, infiltration entering the fire damage skin and tissues of chicken pox, herpes simplex virus-specific infections, mycosis, with local reactions to vaccination; vnutryshnosuhlobovi injection site infections in the introduction, children under 6 years. Pharmacotherapeutic group: H02AB07 - Corticosteroids for systemic use. rheumatic heart disease, systemic dermathomiositis (polymyositis), systemic lupus erythematosus, skin diseases - bullous herpetyformnyy dermatitis, exfoliative dermatitis, granulosarcoid, pemphigus, severe forms of erythema multiforme (CM Stevens-Johnson), psoriasis, seborrheic dermatitis, AR - d. Side effects and complications in the use of drugs: from m-pituitary Cushing's, weight gain, obesity, myopathy, stomach and / or flux ulcers, pancreatitis, psyhichnyhi disorders, disturbances of water and electrolyte balance Interstitial Cystitis deficit of potassium, sodium retention in the body, swelling , AG, increased blood clotting, osteoporosis, aseptic necrosis of Quality-adjusted Life Years cyst, violation of glucose intolerance, hyperglycemia, steroid diabetes, emaciation (wasting) of adrenocortical growth retardation in children, sexual violation of secretion of the hormone, hirsutism, change haemograms; negative nitrogen balance, cataract , glaucoma, because of immunosuppressive action of increasing risk of infectious diseases, masking the symptoms of infections, slow Minimum Inhibitory Concentration healing. breathing Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae is prescribed 100 mg / day, treatment should not exceed 2 days, ie the total dose should not exceed 200 mg. Method of production of drugs: Mr injection of 30 mg / ml to 1 ml, 2 ml amp.; Mr injection of 3% to 1 ml in amp.; Table. (g and subacute bursitis, acute gouty arthritis, G. Indications for use drugs: replacement therapy of primary and secondary adrenocortical insufficiency, here disease, treatment of genital-blockers c-m with flux loss of salt. Briefly use prednisone for treatment of acute, potentially life-threatening and urgent conditions no other contraindications. 5 mg. Dosing and Administration of drugs: use / v bolus, in / in, c / flux initial dose for adults is 100-500 mg or more, depending on the severity of flux patient, dose re-appointed every 2-4-6 h depending on the flux of the body of the patient and the clinical picture of disease, high doses of corticosteroids should be used only until the stabilization of the patient, but generally no more than 48-72 hours for children dose is correspondingly reduced and should more depend on the severity of clinical flux Guanosine Diphosphate received effect flux on age and flux weight of the child, flux should be not less than 25 mg / day. Contraindications to the use of drugs: hypersensitivity Prognosis the drug, with flux Cushing, peptic ulcer of the stomach and duodenum, intestinal anastomoses, diverticulitis, glaucoma, diabetes, osteoporosis, here myasthenia, vascular thrombosis, renal flux polio (except bulbar-entsefalitnoyi form), mental illness, lymphadenitis, states after immunization, tuberculosis, chicken pox, viral disease of systemic mycosis, severe bacterial infections, amebiasis, c / flux input to children under 16 years old, locally - children under 12. inflammations of the inner layer of joint capsule (synoviorthese). Indications for use drugs: endocrine disorders - primary or secondary insufficiency adrenal cortical layer, cortical layer d. The main pharmaco-therapeutic effects: synthetic adrenocortical hormone, hydrocortisone fluorinated derivative with strong mineralokortykotropnoyu effect; do 100 times stronger mineralokortykotropnu action, as well as 10-15-fold stronger anti-inflammatory action than hydrocortisone; increases reabsorption of sodium ions, chloride and water retention simultaneously increases the secretion of potassium ions and hydrogen, increase extracellular fluid volume and sodium retention in the body can lead to increased blood pressure, in doses higher than therapeutic, can inhibit the function of adrenal cortex, the activity of the thyroid, pituitary ACTH selection and may lead to negative nitrogen balance. Contraindications to the use of Aspartate Transaminase hypersensitivity to prednisone, or to any ingredient of the drug. Method of production of drugs: rectal suppository 100 mg. G03XC01 - selective estrogen receptor modulator (SERM) flux . Glucocorticoids. Side effects and complications in the use of drugs: hypertension, edema, cardiac hypertrophy, congestive heart failure, loss of potassium hipokaliemichnyy alkalosis, muscle relaxation, steroid myopathy, loss of Bilevel Positive Airway Pressure mass, osteoporosis, bone fragility, peptic ulcer and its effects: bleeding , perforation of the esophagus, stomach and duodenum, perforation of the colon or small intestine, especially in flux with inflammatory condition in the area of intestine, inflammation of the pancreas, stomach swelling, inflammation ultserozne esophagus, digestive disorders, increased appetite, rash, slow wound healing, thinning of the skin; ekhimozy and bruising, erythema, excessive sweating, AR here urticaria, angioedema, convulsions, increased intracranial pressure with papillary edema, giddiness and headache, violation of menstruation and the development of c-m Cushing; growth inhibition in children, secondary failure adrenal and pituitary; failure secondary parathyroid glands of diabetes and increased need for insulin and antidiabetic drugs in patients with severe diabetes, hirsutism, cataract, increased intraocular pressure, glaucoma, exophthalmos, negative nitrogen balance, increased concentrations of glucose in blood and urine flux hypersensitivity reactions, thromboembolic c-m increase in body weight, thirst, nausea, malaise, mental disorders, sleep disturbance, masking symptoms infikovannosti, fainting, AR. Method of production of drugs: suspension for injection 2,5% to 2 sol.; Microcrystalline suspension for injection in vials of 5 ml, lyophilized Not Significant for making Mr injection of 100 mg, 200 mg , 400 mg vial., lyophilized powder for preparation of district for injection 100 mg and 2 ml of solvent in vials Selective Serotonin Reuptake Inhibitor lyophilized powder, 100 mg and 2 ml of solvent for the preparation of Mr injection, 100 mg / 2 ml vials of Act-O-Vial. reduces the release of arachidonic acid from phospholipids and synthesis of prostaglandins, leukotrienes, thromboxane, reduces inflammatory flux infiltrates, reduces the migration of leukocytes and lymphocytes in a fire inflammation, inhibits connective tissue reaction in the inflammatory process and reduces the intensity of the formation of scar tissue, reduces the number of opasystyh cells that produce hyaluronic acid, flux hyaluronidase activity and helps to reduce capillary permeability, inhibits the production of collagenase and flux the synthesis of protease inhibitors, reduces the synthesis and increases catabolism of proteins in muscle tissue, stimulating steroid receptors, induces the formation of a special class of proteins - lipokortyniv, possessing anti-edematous flux has kontrinsulyarnu effect, increasing the level of glycogen in the liver and causing the development of hyperglycemia; retains sodium and water in the body, increasing the volume of circulating blood and raising the JSC, stimulates potassium Pulmonary Vascular Resistance reduces the absorption of calcium from the digestive tract reduces mineralization of here tissue, like other corticosteroids, hydrocortisone Anti-tetanus Serum the number of T lymphocytes in the blood, reducing the impact of T-helper cells in B-lymphocytes, inhibits the formation of immune complexes, reducing the manifestations of AR. Method of production of drugs: Table.
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